The main symptom of astigmatism is blurring. People can also experience headaches and eyestrain. Parents can notice that a child may have astigmatism when the child can see some part of a pattern or picture more clearly than others. For example, lines going across may seem clearer than lines going up and down.

Regular astigmatism can be caused by the weight of the upper eyelid resting on the eyeball creating distortion, surgical incisions in the cornea, trauma or scarring to the cornea, the presence of tumors in the eyelid, or a developmental factor. Irregular astigmatism can be caused by scarring or keratoconus. Keratoconus is a condition in which the cornea thins and becomes cone shaped. It usually occurs around puberty and is more common in women. Although the causes of keratoconus are unknown, it may be hereditary or a result of chronic eye rubbing, as in people with allergies. The center of the cone may not be in line with the center of the cornea. Diabetes can play a role in the development of astigmatism. High blood sugar levels can cause shape changes in the lens of the eye. This process usually occurs slowly and, often, is only noticed when the diabetic has started treatment to control their blood sugar. The return to a more normal blood sugar allows the lens to return to normal and this change is sometimes noticed by the patient as farsightedness. Because of this, diabetics should wait until their blood sugar is under control for at least one month to allow vision to stabilize before being measured for eyeglasses.