Why are gram-positive bacteria typicaly more resistant than gram-negative bacteria to antibiotics, that disrupt plasma membranes, such as polymyxin B?
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Anonymous
ANSWERS: 1
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gram positive bacteria have a cell wall surrounding the organism, including the plasma membrane. a plasma membrane is usually made up of lipids, which can easily move around to let other molecules in. meanwhile, a cell wall is a more rigid structure that is not as easily broken. the best way i understand it is by imagining someone wearing a suit of armor. the armor is like the cell wall, which protects the person(or bacteria) from arrows (or the antibiotics). the person with armor is better protected than another person without any armor. likewise, a bacterium with a cell wall has more protection than one with only a plasma membrane.
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